Forensic toxicology is a cornerstone of investigations involving sudden death, drug-facilitated crimes, and driving under the influence (DUI). Traditionally, laboratories rely on standard biological specimens such as blood or urine, often collected with preservatives like sodium fluoride. However, in many complex cases, these conventional specimens are not available.
This is where non-traditional toxicology testing becomes an essential tool in the forensic toolkit.
When Traditional Specimens Aren’t Available
In real-world investigations, circumstances often prevent the collection of typical toxicological samples. In such cases, forensic laboratories are being called upon to assess whether items like clothing, bedding, vehicle upholstery, or personal hygiene products stained with biological fluids are suitable for toxicological analysis.
Though comprehensive method validation for every object type is impractical, this challenge should not discourage forensic professionals from pursuing alternative testing routes.
A Practical and Robust Testing Approach
A qualitative method has been developed to accurately identify drugs in biological fluids on or within non-traditional evidence. This approach ensures the reliability and scientific integrity of test results without the need for full validation on every item type.
The process includes:
– Tailored sample preparation techniques
– Use of specialised quality control samples derived from the items themselves
– Defined analytical acceptance criteria
– Clear reporting protocols
This methodology supports accurate, consistent findings even with unconventional evidence.
Real-World Case Examples from Forensic Investigations
This testing strategy has already delivered positive results in numerous cases:
– Zolpidem detected in vomit stains on clothing
– Cocaine, codeine, acetaminophen, caffeine, and cocaine metabolites found in stains on bedding
– Diphenhydramine, doxylamine, and dextromethorphan identified in mattress pad covers
These results highlight the method’s ability to detect a wide range of substances, including illicit drugs, prescription medications, novel psychoactive substances (NPS), and over-the-counter medicines.
Why This Matters in Forensic Toxicology
This innovative toxicology approach provides significant advantages in forensic science:
– Reveals past drug exposure when traditional samples are missing
– Associates drugs with specific locations such as a crime scene or vehicle
– Aids in missing person investigations by offering biological evidence from found items
– Supports legal outcomes by expanding the types of evidence that can be analysed
Final Thoughts: A Fit-for-Purpose Approach for Modern Investigations
As forensic science evolves, non-traditional toxicology testing is proving essential for expanding evidence collection in drug-related cases. Forensic laboratories across the UK can now apply a scientifically sound, flexible methodology to help solve cases that would otherwise lack toxicological data.
Whether it’s linking a drug to a specific scene or providing answers when a person is missing, these innovative methods are making a measurable impact in forensic toxicology.

 
 